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1

Pharmacokinetic studies of mofezolac. II: Identification of metabolites and biotransformation of mofezolac in various animals.

SHINDO, Takashi, KAWAUCHI, Takashi, MASUDA, Hirotoshi, SUZUKI, Takashi, MINAMI, Yoshinori, MANIWA, Madoka, KAWAGUCHI, Yasuro

Journal:

Drug Metabolism and Pharmacokinetics

Year:

1990

Language:

english

File:

PDF, 9.64 MB

english, 1990

2

Reduction of 5-fluorouracil (5-FU) gastrointestinal (GI) toxicity resulting from the protection of thymidylate synthase (TS) in GI tissue by repeated simultaneous administration of potassium oxonate (Oxo) in rats

Kunihiro Yoshisue, Kazue Hironaga, Syuji Yamaguchi, Akira Yamamoto, Sekio Nagayama, Yasuro Kawaguchi

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 119 KB

english, 2000

3

Occurrence of autoimmune antibodies to liver microsomal proteins associated with lethal hepatitis in LEC rats: effects of TJN-101 ((+)-(6S,7S,R-biar)-5,6,7,8-tetrahydro-1,2,3,12-tetramethoxy-6,7-dimethyl-10,11-methylenedioxy-6-dibenzo[a,c]cyclooctenol) on the development of hepatitis and the autoantibodies

Yokoi, Tsuyoshi, Nagayama, Sekio, Kajiwara, Rieko, Kawaguchi, Yasuro, Aizawa, Tatsuo, Otaki, Yumiko, Aburada, Masaki, Kamataki, Tetsuya

Journal:

Toxicology Letters

Year:

1995

Language:

english

File:

PDF, 343 KB

english, 1995

4

Occurrence of autoimmune antibodies to liver microsomal proteins in association with fulminant hepatitis in the LEC strain of rats

Sekio Nagayama, Ryuji Kitamura, Tsuyoshi Yokoi, Yasuro Kawaguchi, Noriyuki Kasai, Noritoshi Takeichi, Hiroshi Kobayashi, Tetsuya Kamataki

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 684 KB

english, 1991

5

Studies on the Fate of 1-(2-Tetrahydrofuryl)-5-fluorouracil (FT-207), a Carcinostatic Agent. III. Absorption, Distribution, Excretion and Metabolism after Rectal Administration of FT-207

FUJII, SETSURO, OKUDA, HIROMICHI, AKAZAWA, AKIRA, YASUDA, YUKIHIRO, KAWAGUCHI, YASURO, FUKUNAGA, YASUFUMI, NISHIKAWA, HIDEO

Journal:

YAKUGAKU ZASSHI

Year:

1975

File:

PDF, 864 KB

1975

6

Structural analysis of suisen glucomannan

Koji Kato, Yasuro Kawaguchi, Takashi Mizuno

Journal:

Carbohydrate Research

Year:

1973

Language:

english

File:

PDF, 566 KB

english, 1973

7

Occurrence of autoantibody to protein disulfide isomerase in rats with xenobiotic-induced hepatitis.

NAGAYAMA, Sekio, YOKOI, Tsuyoshi, KAWAGUCHI, Yasuro, KAMATAKI, Tetsuya

Journal:

The Journal of Toxicological Sciences

Year:

1994

File:

PDF, 836 KB

1994

8

Occurrence of autoantibody to protein disulfide isomerase in patients with hepatic disorder.

NAGAYAMA, Sekio, YOKOI, Tsuyoshi, TANAKA, Hirotoshi, KAWAGUCHI, Yasuro, SHIRASAKA, Tomonobu, KAMATAKI, Tetsuya

Journal:

The Journal of Toxicological Sciences

Year:

1994

File:

PDF, 766 KB

1994

9

Determination of 3′-C-ethynylcytidine in human plasma and urine by liquid chromatographic-electrospray ionization tandem mass spectrometry

Kazuaki Matsuoka, Ryuichi Kitamura, Eiji Matsushima, Yasuro Kawaguchi

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2003

Language:

english

File:

PDF, 285 KB

english, 2003

10

Prediction of the pharmacokinetics of cefodizime and cefotetan in humans from pharmacokinetic parameters in animals.

MATSUSHITA, Hitoshi, SUZUKI, Hiroshi, SUGIYAMA, Yuichi, SAWADA, Yasufumi, IGA, Tatsuji, HANANO, Manabu, KAWAGUCHI, Yasuro

Journal:

Journal of Pharmacobio-Dynamics

Year:

1990

File:

PDF, 856 KB

1990

11

Studies on the Fate of 5-Fluoro-1, 3-bis (tetrahydro-2-furanyl)-2, 4-pyrimidinedione (FD-1), a New Antitumor Agent. I. Absorption, Distribution, Excretion and Metabolism of FD-1 administered orally to Rats

KAWAGUCHI, YASURO, NAKAMURA, YOSHIMASA, SATO, TOSHIYUKI, TAKEDA, SETSUO, MARUNAKA, TERUYOSHI, FUJII, SETSURO

Journal:

YAKUGAKU ZASSHI

Year:

1978

File:

PDF, 1.12 MB

1978

12

Efficacy and Safety of Insulin Glargine 300 U/mL versus Insulin Degludec in Patients with Type 2 Diabetes: A Randomized, Open-Label, Crossover Study Using Continuous Glucose Monitoring Profiles

Kawaguchi, Yuji, Sawa, Jun, Sakuma, Noriko, Kumeda, Yasuro

Journal:

Journal of Diabetes Investigation

Year:

2018

Language:

english

File:

PDF, 429 KB

english, 2018

13

Dehydrocoupling Reactions of Borane−Secondary and −Primary Amine Adducts Catalyzed by Group-6 Carbonyl Complexes: Formation of Aminoboranes and Borazines

Kawano, Yasuro, Uruichi, Mikio, Shimoi, Mamoru, Taki, Seitaro, Kawaguchi, Takayuki, Kakizawa, Taeko, Ogino, Hiroshi

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 2.10 MB

english, 2009

14

Comparative Analysis of In Vitro and In Vivo Pharmacokinetic Parameters Related to Individual Variability of GTS-21 in Canine

Azuma, Ryotaro, Komuro, Masahito, Kawaguchi, Yasuro, Okudaira, Kazuho, Hayashi, Masahiro, Kiwada, Hiroshi

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2002

Language:

english

File:

PDF, 263 KB

english, 2002

15

Radioimmunoassay for dexamethasone 17,21-dipropionate and its metabolites in plasma and urine after topical application

Yukitaka Miyachi, Masaru Ishihara, Satoshi Kurihara, Masahiko Yoshida, Hirotoshi Masuda, Masahito Komuro, Kazuki Taira, Yasuro Kawaguchi

Journal:

Year:

1988

Language:

english

File:

PDF, 710 KB

english, 1988

16

Suicidal inactivation of human dihydropyrimidine dehydrogenase by (E)-5-(2-bromovinyl)uracil derived from the antiviral, sorivudine

Kenichiro Ogura, Takahito Nishiyama, Hiroaki Takubo, Atsushi Kato, Haruhiro Okuda, Kazuhito Arakawa, Masakazu Fukushima, Sekio Nagayama, Yasuro Kawaguchi, Tadashi Watabe

Journal:

Year:

1998

Language:

english

File:

PDF, 106 KB

english, 1998

17

Identification of protein disulfide isomerase and calreticulin as autoimmune antigens in LEC strain of rats

Yokoi, Tsuyoshi, Nagayama, Sekio, Kajiwara, Rieko, Kawaguchi, Yasuro, Horiuchi, Ryuya, Kamataki, Tetsuya

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1993

Language:

english

File:

PDF, 896 KB

english, 1993

18

Pharmacokinetic Studies of 6-amidino-2-naphthyl 4-((4,5-dihydro-1H-imidazol-2-yl)amino) benzoate dimethanesulfonate (FUT-187). (1). Absorption, Distribution and Excretion after a Single Oral Administration to Rats.

KOMATSU, Shinzo, KUROTORI, Masayuki, IWAMOTO, Satomi, SUGIYAMA, Satoshi, SHIBUYA, Masaoki, KAWAGUCHI, Yasuro

Journal:

Drug Metabolism and Pharmacokinetics

Year:

1992

File:

PDF, 8.94 MB

1992

19

Efficacy and Safety of Tofogliflozin and Ipragliflozin for Patients with Type-2 Diabetes: A Randomized Crossover Study by Flash Glucose Monitoring

Kawaguchi, Yuji, Sawa, Jun, Kumeda, Yasuro

Journal:

Diabetes Therapy

Year:

2020

File:

PDF, 408 KB

2020

20

Improvement in precision of the liquid chromatographic–electrospray ionization tandem mass spectrometric analysis of 3′-C-ethynylcytidine in rat plasma

Ryuichi Kitamura, Kazuaki Matsuoka, Eiji Matsushima, Yasuro Kawaguchi

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2001

Language:

english

File:

PDF, 92 KB

english, 2001

21

Pharmacokinetic studies of mofezolac. IV: Metabolism in rats after oral administration of 14C-mofezolac.

MASUDA, Hirotoshi, SUZUKI, Takashi, KAWAUCHI, Takashi, SHINDO, Takashi, KAWAGUCHI, Yasuro

Journal:

Drug Metabolism and Pharmacokinetics

Year:

1990

File:

PDF, 2.88 MB

1990

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